Home > Blossary: Addictive Drugs
A blossary of terms related to addictive drugs.

Category: Law

20 Terms

Created by: Silentchapel

Number of Blossarys: 95

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Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use.

Domain: Law enforcement; Category: Drug trafficking

Petidină este indicat pentru tratamentul de moderată până la severă, dureri, şi este livrat ca o clorhidrat de sare in tablete, ca un sirop, sau prin injectare intramusculară, subcutanat sau intravenos. Pentru o mare parte a secolului XX, Petidină a fost opioide de alegere pentru multi medici; în 1975 60% din medici este prescris pentru durere acută şi 22% pentru durere cronică severă. Comparativ cu morfină, Petidină a fost gândit pentru a fi mai sigur, transporta un risc mai mic de dependenţă şi pentru a fi superioare în tratarea durerii asociate cu spasme biliare sau colică renală datorita efectelor sale putative anticolinergic. A fost descoperit mai târziu că acestea au fost toate miturile şi efectuarea unui risc cel puţin egale de dependenta, posedat fără efecte avantajoase spasmul biliare sau colică renală, comparativ cu alte opioide şi că, datorită metabolitului său toxic, norpethidine, a fost mai toxic decât alte opioide, mai ales în timpul utilizarea pe termen lung.

Domain: Law enforcement; Category: Drug trafficking

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