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A phenomenon in which the disease phenotype depends on which parent passed on the disease gene. For instance, both Prader-Willi and Angelman syndromes are inherited when the same part of chromosome 15 is missing. When the father's complement of 15 is missing, the child has Prader-Willi, but when the mother's complement of 15 is missing, the child has Angelman syndrome..
Industry:Biology
A description of a specific chromosome that uses defined mutations --specific deleted areas in the genome-- as 'biochemical signposts,' or markers for specific areas..
Industry:Biology
The synthesis of an RNA copy from a sequence of DNA (a gene); the first step in gene expression.
See also: translation.
Industry:Biology
During meiosis each of the two copies of a gene is distributed to the germ cells independently of the distribution of other genes.
See also: linkage.
Industry:Biology
A laboratory process used on isolated molecules or microbes to cause mutations and identify subsequent adaptations to novel environments..
Industry:Biology
A protein that binds to regulatory regions and helps control gene expression..
Industry:Biology
In genetics, to receive genetic material from parents through biological processes..
Industry:Biology
A discrete portion of a protein with its own function. The combination of domains in a single protein determines its overall function..
Industry:Biology
A chromosome abnormality in which a piece of DNA is incorporated into a gene and thereby disrupts the gene's normal function.
See also: chromosome, DNA, gene, mutation.
Industry:Biology
